Aspartame Aspartame is synthesized by chemically coupling aspartic acid and phenylalanine methyl ester, used as a high-intensity non-caloric sweetener (INS 951) that provides clean sucrose-like sweetness without bitter aftertaste or gastrointestinal effects, ideal for sugar-reduced and diabetic formulations. In the food industry, it delivers sugar-like temporal profile and synergizes with bulking agents like maltodextrin for optimal mouthfeel in beverages, confections, and tabletop applications.